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Spyre Therapeutics, Inc.SYRE

Close of Friday, October 23, 2026 · Spyre Therapeutics, Inc. is trading above its Pivot, OnlyAlpha's long-term trend line.

Price
$90.32
vs its Pivot
+26.2%
OnlyAlpha Score
47
Trend
Above its Pivot
$107.81$17.37
Last 12 months. Solid line: price. Dashed green: the Pivot.

Returns

1 monthYear to date1 year3 years / yr5 years / yr
+3.7%+175.7%+306.7%——

No dividend in the last 12 months.

Who runs and owns it

In these funds

IBB · 0.51%IWM · 0.23%

Big investors that own it (latest 13F)

Perceptive Advisors6.0% of holdings
OrbiMed0.3% of holdings
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